Ľupták M, Michaličková D, Fišar Z, Kitzlerová E, Hroudová J. Novel approaches in schizophrenia-from risk factors and hypotheses to novel drug targets. World J Psychiatr 2021; 11(7): 277-296 URL: https://www.wjgnet.com/2220-3206/full/v11/i7/277.htm DOI: https://dx.doi.org/10.5498/wjp.v11.i7.277
“Overall, opiod prescribing rates have been shown to decrease in some states after implementation of PDMPs, but no significant changes have been found in others. Studies on the effects of PDMPs on opiod overdoses have similarly been mixed with some studies finding no chance in overdose following PDMP implementation, and others finding an increase in overdose. In addition, there has been considerable concern among researchers that the rise in heroin use and overdose starting in 2010 may have been an unintended consequence of policies like the PDMP that reduced the supply of prescription opioids for non-medical use.